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Hand, foot and mouth disease in Nagpur
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Abstract:
Hand, foot and mouth disease (HFMD) is a viral infection of children caused by Coxsackie virus-A16, a type of enterovirus closely related with the virus that causes herpangina. Although seen worldwide, it is not common in India. Hand, foot and mouth disease is sporadically reported from India as a mild illness. This report describes four cases of HFMD from Nagpur, Central India, seen between September 2005 and April 2006. All patients presented with a mild febrile prodrome followed by the appearance of aphthous-like oral ulcers and vesicular lesions on the hands and feet. All cases were clinically diagnosed. Coxsackie virus A16 was isolated from the serum of one of the patients. All the patients were in the age group of 3-5 years from different schools. It was a mild illness and all the four patients recovered without any complication. There were no secondary cases in the families.
Insights
Hand, foot, and mouth disease (HFMD), a viral infection, is uncommon in India. This report details four mild pediatric cases in Nagpur, all recovering without complications.
Area of Science:
- Pediatrics
- Virology
- Infectious Diseases
Background:
- Hand, foot, and mouth disease (HFMD) is a common childhood viral illness globally, typically caused by Coxsackievirus A16.
- While prevalent worldwide, HFMD is infrequently reported in India, often presenting as a mild condition.
Purpose of the Study:
- To describe clinical features and outcomes of HFMD cases in Central India.
- To document the occurrence of Coxsackievirus A16 in a pediatric population in India.
Main Methods:
- Clinical case reporting of four pediatric patients diagnosed with HFMD.
- Viral isolation of Coxsackievirus A16 from patient serum.
Main Results:
- Four children aged 3-5 years presented with mild febrile prodrome, oral ulcers, and vesicular lesions on hands and feet.
- Coxsackievirus A16 was identified in one patient; all cases resolved without complications.
- No secondary transmission was observed within families.
Conclusions:
- HFMD caused by Coxsackievirus A16 can occur sporadically in India, presenting as a mild illness in young children.
- Clinical diagnosis is feasible, and the disease appears to have a favorable prognosis in this region.
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