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Related Concept Videos

Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Classification of Epithelial Tissues: Glandular Epithelium01:20

Classification of Epithelial Tissues: Glandular Epithelium

The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Bone Cells and Tissue01:30

Bone Cells and Tissue

Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the periosteum and...
Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
Classification of Epithelial Tissues: Simple Epithelium01:30

Classification of Epithelial Tissues: Simple Epithelium

Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...

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Related Experiment Video

Updated: Jul 6, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

[Benign epithelial odontogenic tumors].

P A Reichart1, G Jundt

  • 1Abteilung Oralchirurgie und Zahnärztliche Röntgenologie, Charité-Universitätsmedizin Berlin. peter-a.reichart@charite.de

Der Pathologe
|April 5, 2008
PubMed
Summary

Benign epithelial odontogenic tumors include ameloblastomas and keratocystic odontogenic tumors, with the latter being most common. Diagnosis relies on location and histology, not immunohistochemistry.

Area of Science:

  • Oral pathology
  • Odontogenic tumors
  • Head and neck oncology

Background:

  • Benign epithelial odontogenic tumors encompass ameloblastoma family variants, squamous odontogenic tumors, calcifying odontogenic tumors, adenomatoid odontogenic tumors, and keratocystic odontogenic tumors.
  • Keratocystic odontogenic tumors are the most prevalent, followed by solid/multicystic ameloblastoma.
  • The etiology remains unknown, but a link to tooth development is evident, with some tumors mimicking this process.

Purpose of the Study:

  • To provide an overview of benign epithelial odontogenic tumors.
  • To highlight diagnostic criteria and treatment considerations.
  • To differentiate the biological behavior and clinical presentation of these tumors.

Main Methods:

  • Review of existing literature and classification systems (e.g., WHO).

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Isolation of Epithelial Cells from Human Dental Follicle
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Isolation of Epithelial Cells from Human Dental Follicle

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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

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Last Updated: Jul 6, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Isolation of Epithelial Cells from Human Dental Follicle
04:07

Isolation of Epithelial Cells from Human Dental Follicle

Published on: November 5, 2021

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

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  • Histopathological analysis and radiographic correlation.
  • Discussion of diagnostic challenges and limitations of immunohistochemistry.

    • Main Results:

    • Keratocystic odontogenic tumors and solid/multicystic ameloblastoma are the most frequent types.
    • Distinct biological behaviors and treatment strategies exist for each tumor type.
    • Diagnosis primarily depends on intraosseous vs. extraosseous localization and histological features.

    Conclusions:

    • Accurate diagnosis of odontogenic tumors requires careful integration of clinical, radiographic, and histological data.
    • Immunohistochemistry is not a reliable diagnostic tool for differentiating these tumors.
    • Understanding the specific characteristics of each tumor type is crucial for appropriate management.