Related Experiment Video
Updated: Jul 6, 2026
06:50
The Use of Mouse Splenocytes to Assess Pathogen-associated Molecular Pattern Influence on Clock Gene Expression
Published on: July 24, 2018
[Has the time arrived for gene expression use at the bedside?]
Véronique D'Hondt1, Martine Piccart, Christos Sotiriou
1Service de médecine interne, Clinique d'oncologie médicale, Institut Jules Bordet, 121, boulevard de Waterloo Bruxelles 1000, Belgique. veronique.dhondt@bordet.be
Bulletin Du Cancer
|April 9, 2008
Summary
Microarray technology revolutionizes breast cancer research by enabling gene expression profiling. This aids in classifying subtypes, predicting outcomes, and understanding cancer progression.
Area of Science:
- Genomics
- Molecular Biology
- Oncology
Context:
- Microarray technology allows simultaneous analysis of thousands of genes.
- Breast cancer research benefits from gene expression profiling for molecular insights.
Purpose:
- To review the current state of gene expression profiling in breast cancer.
- To discuss the potential impact of this technology on patient management.
Summary:
- Gene expression profiling has led to molecular classification of breast cancer into clinically relevant subtypes.
- It provides tools for predicting disease outcome and treatment response.
- Insights into carcinogenesis and metastatic pathways are enhanced.
Impact:
- Potential to significantly improve breast cancer patient management.
- Addresses the limitations and highlights the promises of gene expression profiling.
- Facilitates personalized medicine approaches in oncology.
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Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
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