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Related Concept Videos

Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Prokaryotic Gene Structure and Organization01:28

Prokaryotic Gene Structure and Organization

Prokaryotic genomes exhibit a streamlined organization of coding and non-coding regions essential for gene expression and protein synthesis. While coding regions contain the genetic instructions for proteins or functional RNAs, non-coding regions regulate the precise transcription and translation of these genes.Coding Regions: Proteins and RNAsThe primary coding regions, known as structural genes, include sequences transcribed into messenger RNA (mRNA) and ultimately translated into...
Prokaryotic Cells01:28

Prokaryotic Cells

Prokaryotes are small unicellular organisms that include the domains — Archaea and Bacteria. Bacteria include many common microorganisms, such as Salmonella and E. coli, while the Archaea include extremophiles that live in harsh environments, such as volcanic springs.
Like eukaryotic cells, all prokaryotic cells are surrounded by a plasma membrane, have genetic material in the form of single, circular DNA, a cytoplasm that fills the interior of the cell, and ribosomes that synthesize proteins.
Prokaryotic Cells01:51

Prokaryotic Cells

Prokaryotes are small unicellular organisms that include the domains—Archaea and Bacteria. Bacteria include many common organisms, such as Salmonella and E. coli, while the Archaea include extremophiles that live in harsh environments, such as volcanic springs.Like eukaryotic cells, all prokaryotic cells are surrounded by a plasma membrane, have genetic material in the form of single, circular DNA, a cytoplasm that fills the interior of the cell, and ribosomes that synthesize proteins. However,...
Prokaryotic cells01:51

Prokaryotic cells

Prokaryotes are small unicellular organisms that include the domains—Archaea and Bacteria. Bacteria include many common organisms, such as Salmonella and E. coli, while the Archaea include extremophiles that live in harsh environments, such as volcanic springs.Like eukaryotic cells, all prokaryotic cells are surrounded by a plasma membrane, have genetic material in the form of single, circular DNA, a cytoplasm that fills the interior of the cell, and ribosomes that synthesize proteins. However,...
Evolution of Microbial Genome01:08

Evolution of Microbial Genome

Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.

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Related Experiment Video

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Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

PGV - Prokaryotic Genome Viewer.

Soma Marla1, Vinay Kumar Singh

  • 1Bioinformatics Centre, Molecular Biology & Genetic Engineering, G. B. Pant University of Agriculture & Technology, Pantnagar, Uttaranchal - 263145, India. ssmarl@yahoo.com

In Silico Biology
|April 9, 2008
PubMed
Summary
This summary is machine-generated.

Prokaryotic Genome Viewer (PGV) is a new tool that creates interactive maps of microbial genomes. This helps researchers easily visualize and analyze gene data from large genomic datasets.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Microbial genome sequencing generates vast amounts of data.
  • Effective computational and visualization tools are needed for data retrieval and analysis.
  • User-friendly tools enhance the examination of gene features and data interpretation.

Purpose of the Study:

  • To introduce Prokaryotic Genome Viewer (PGV), a novel Java-based web application.
  • To provide researchers with an efficient tool for mapping and visualizing prokaryotic genome data.
  • To facilitate detailed examination of genomic features and data inferences.

Main Methods:

  • Development of a Java-based web application named Prokaryotic Genome Viewer (PGV).
  • Implementation of interactive features including mouse rollover for feature labeling, multi-fold zooming, and image rotation.
  • Integration of hyperlinking to external information resources.
  • Capability to generate circular chromosome maps from user-supplied sequence data.

Main Results:

  • PGV generates high-quality, interactive circular chromosome maps.
  • The tool offers intuitive user interactions for data exploration.
  • Instantaneous map generation is possible with user-provided sequence data.
  • Facilitates efficient analysis of prokaryotic genomic features.

Conclusions:

  • PGV is an effective and user-friendly tool for prokaryotic genome data visualization and analysis.
  • The interactive features enhance researchers' ability to explore and understand genomic information.
  • PGV supports efficient retrieval and interpretation of data from large genomic databases.