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Catheter locking-solution spillage: theory and experimental verification
1hdp@aon.at
Unlabelled:
A theory was developed allowing the prediction of the spillage volume after injection of locking solution into a catheter. This theory was corroborated by in-vitro measurements using colorized fluid injected automatically by a micropump into a stirred container with clear fluid. The amount of spilled solution was measured with a fiberoptic spectrometer equipped with a dip probe. Straight cylindrical tubing was used as catheter.
Results:
The theory predicts the beginning of spillage when 50% of the catheter filling volume is injected. When the nominal filling volume is injected, 25% of the solution is spilled and the mean concentration at the catheter tip is 50% of the locking solution concentration.
Experiments:
Spillage was slightly less than predicted (20-25% at nominal filling volume). During the experiments it was recognized that a small air bubble trapped in the Luer connection during connection reduces the spillage volume to 10-15%.
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