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Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
Published on: June 21, 2024
[Renal parenchymal disease: histopathologic-sonographic correlation].
Nordeval Cavalcante Araújo1, Lilimar da Silveira Rioja, Maria Alice Puga Rebelo
1Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. nordeval@oi.com.br
Revista Da Associacao Medica Brasileira (1992)
|April 9, 2008
Summary
Increased kidney cortical echogenicity on ultrasound is a sensitive marker for renal parenchymal disease. Specific histological lesions, not just severity, correlate with echogenicity changes in patients.
Area of Science:
- Nephrology
- Radiology
- Pathology
Background:
- Renal parenchymal disease diagnosis often requires biopsy.
- Sonography offers a non-invasive imaging modality for kidney assessment.
Purpose of the Study:
- To correlate kidney sonography findings with histological lesions and clinical data in renal parenchymal disease.
- To analyze the relationship using multivariate logistic regression.
Main Methods:
- Evaluated 154 patients with clinical, laboratory, sonographic, and biopsy data.
- Graded cortical echogenicity relative to liver/spleen.
- Assessed histological lesions (e.g., mesangial proliferation, interstitial infiltrate) and their severity.
Main Results:
- Cortical echogenicity grade 0 was associated with less interstitial infiltrate, fibrosis, sclerosis, edema, and lower creatinine.
- Mesangial proliferation, hypertension, and normal thickness predicted grade 1 echogenicity.
- Fibrosis, edema, creatinine, and thin parenchyma predicted grade 2 echogenicity.
Conclusions:
- Increased cortical echogenicity is a sensitive indicator of renal parenchymal disease.
- Specific histological lesions, rather than severity alone, drive echogenicity changes.
- Interstitial edema significantly potentiates the effect of interstitial fibrosis on echogenicity.
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