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Updated: Jul 6, 2026

Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
Published on: September 18, 2011
[Acute spinal cord ischemia following deep injection therapy of the neck]
M Dafotakis1, G R Fink, C Schlangen
1Institut für Neurowissenschaften und Biophysik - Medizin, Forschungszentrum Jülich, Leo-Brandt-Strasse 1, 52428, Jülich. m.dafotakis@fz-juelich.de
Abstract:
We report the case of a 40-year-old woman suffering from neck pain due to mild cervical spine injury. During conventional faceted infiltration therapy with crystalline steroids, the patient developed weakness in both arms and paresthesia of the left arm. While the weakness resolved within a few seconds, a mild deficit in motor coordination and paresthesia of the left arm were still present after 2 months. T2-weighted magnetic resonance imaging of the cervical spine depicted a small hyperintense lesion at the C6 level most likely reflecting embolic infarction due to injection of crystalline steroids into a myelon-feeding artery, which has of late repeatedly been reported. We discuss potential pathomechanisms of this very rare complication and give a review of the literature.
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