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Mário Geraldo de Carvalho1, Lucilene Faustina de Oliveira Cândido, Patrícia Miranda da Costa

  • 1Departamento de Química, Instituto de Ciências Exatas, Universidade Federal Rural do Rio de Janeiro, BR 465, Km.7, Seropédica, RJ, 23890-000, Brazil. mgeraldo@ufrrj.br

Journal of Natural Medicines
|April 9, 2008
PubMed

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Esters can be hydrolyzed to carboxylic acids under acidic or basic conditions. Base-promoted hydrolysis of esters is a nucleophilic acyl substitution reaction in which esters react with an aqueous base, followed by an acid to give carboxylic acids. This reaction is also known as saponification because it forms the basis for making soaps from fats.
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