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Related Concept Videos

Reflex Activity01:08

Reflex Activity

A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort.
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...

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Related Experiment Video

Updated: Jul 6, 2026

Terminal H-reflex Measurements in Mice
05:38

Terminal H-reflex Measurements in Mice

Published on: June 16, 2022

The H-reflex as a probe: pathways and pitfalls.

Maria Knikou1

  • 1Health Sciences Doctoral Programs, City University of New York, Staten Island, NY 10314, USA. knikou@mail.csi.cuny.edu

Journal of Neuroscience Methods
|April 9, 2008
PubMed
Summary

The Hoffmann (or H) reflex is a sensitive probe for studying the human central nervous system. Understanding its complex neural mechanisms is crucial for accurate neurophysiological studies and rehabilitation.

Area of Science:

  • Neuroscience
  • Human Physiology
  • Motor Control

Background:

  • The Hoffmann (or H) reflex is a key non-invasive tool for studying sensorimotor integration and central nervous system plasticity.
  • Understanding the H-reflex's neurophysiological properties is essential to avoid experimental pitfalls.
  • Spinal inhibitory circuits, including reciprocal, presynaptic, and Ib inhibition, can be assessed using the H-reflex.

Purpose of the Study:

  • To review the neurophysiological properties of the H-reflex.
  • To discuss the spinal inhibitory circuits and neuronal pathways assessable via the H-reflex.
  • To highlight the importance of comprehensive characterization of spinal circuits for neurological injury rehabilitation.

Main Methods:

  • Review of neurophysiological properties of the H-reflex.

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  • Analysis of spinal inhibitory circuits and neuronal pathways.
  • Discussion of the H-reflex's application in human experimental studies.

    • Main Results:

    • The H-reflex is a sensitive measure influenced by complex, synchronous neural mechanisms.
    • Reciprocal, presynaptic, and Ib inhibition interact during movement, complicating isolated assessment.
    • Neurophysiological findings from H-reflex studies are critical for developing rehabilitation protocols.

    Conclusions:

    • The H-reflex is a valuable tool for assessing human interneuronal circuit excitability.
    • Recognizing and addressing the H-reflex's limitations enhances its utility in research and clinical practice.
    • Comprehensive understanding of the H-reflex is vital for advancing rehabilitation strategies post-neurological injury.