Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Body Temperature01:07

Body Temperature

Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C (97–99°F), remaining relatively stable...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A French observational study of botulinum toxin use in the management of children with cerebral palsy: BOTULOSCOPE.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2011
Same author

[Interest of Percussionator in neuromuscular patients. Eight years experience in three quadriplegic ventilator-dependant children].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2009
Same author

[Follow-up network for newborns at risk for handicap in a French region].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2007
Same author

[Medical aspects of commercial air travel].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2006
Same author

[Dietary water intoxication: a preventable pathology].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2006
Same author

Prophylactic ibuprofen versus placebo in very premature infants: a randomised, double-blind, placebo-controlled trial.

Lancet (London, England)·2004

Related Experiment Video

Updated: Jul 6, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
08:22

A Preclinical Model of Exertional Heat Stroke in Mice

Published on: July 1, 2021

[Heat stroke and topiramate].

T Boussemart1, V Flurin, F Labay-Bruneau

  • 1Unité de réanimation pédiatrique, service de pédiatrie centre hospitalier du Mans, 194 avenue Rubillard, Le Mans cedex, France. tboussemart@ch-lemans.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|April 9, 2008
PubMed
Summary
This summary is machine-generated.

Heatstroke is rare in children but can be worsened by certain medications. A 10-year-old epileptic patient on topiramate developed heatstroke, suggesting this drug may increase risk.

More Related Videos

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
06:58

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

Published on: July 12, 2021

Related Experiment Videos

Last Updated: Jul 6, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
08:22

A Preclinical Model of Exertional Heat Stroke in Mice

Published on: July 1, 2021

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
06:58

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

Published on: July 12, 2021

Area of Science:

  • Environmental medicine
  • Pediatric neurology
  • Clinical pharmacology

Background:

  • Heatstroke, a severe disorder from environmental hyperthermia, is uncommon in pediatric populations.
  • Predisposing medical conditions and certain medications can elevate the risk of heatstroke.
  • Epilepsy is a neurological disorder often managed with various medications.

Observation:

  • A 10-year-old child with epilepsy, treated with topiramate, experienced heatstroke.
  • Topiramate is known to potentially cause hypohydrosis (reduced sweating) and hyperthermia (elevated body temperature).

Findings:

  • The patient's presentation suggests a potential link between topiramate use and the development of heatstroke.
  • Hypohydrosis and hyperthermia induced by topiramate may be critical factors contributing to heatstroke in susceptible individuals.

Implications:

  • Topiramate may represent a significant risk factor for heatstroke in pediatric patients, particularly those with epilepsy.
  • Clinicians should consider medication side effects, such as those from topiramate, when evaluating children with hyperthermia.
  • Further research is warranted to confirm the association between topiramate and heatstroke risk in children.