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Updated: Jul 6, 2026
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Duodenum-preserving local excision of a gastrointestinal stromal tumor
Chandika A H Liyanage1, Sanjaya Abeygunawardhana, Sumudu Kumarage
1Department of Surgery, University of Kelaniya Medical School, Ragama, Sri Lanka. chandikaliyanage@hotmail.com
Background:
Duodenal gastrointestinal stromal tumors (GISTs) are rare. Because of the complex anatomy of the duodenum, the methods of resection of these tumors are controversial and diverse.
Methods:
We report a case of a duodenal GIST in the anterolateral wall of the second part of the duodenum, which was successfully managed by local excision. The surgery was facilitated by preoperative mapping with Indian ink and navigation by endoscopy to assess the adequacy of resection and to avoid injury to the ampulla.
Result:
Reconstruction was successful with a duodenojejunostomy and protected by a nasoduodenal drain.
Conclusion:
The patient had no postoperative complications and the tumor was confirmed to be a GIST of the duodenum successful with an adequate resection margin.