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Updated: Jul 6, 2026
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
[Heart failure with preserved ejection fraction]
1Service de cardiologie A, CHU Rangueil, TSA 50032, F-31059 Toulouse Cedex 9, France. galinier.m@chu-toulouse.fr
Presse Medicale (Paris, France : 1983)
|April 11, 2008
Summary
Heart failure with preserved ejection fraction (HFPEF) presents with heart failure symptoms and normal ejection fraction. Diagnosis is aided by natriuretic peptides and echocardiography, with similar prognosis and treatment to systolic heart failure.
Area of Science:
- Cardiology
- Internal Medicine
Context:
- Heart failure with preserved ejection fraction (HFPEF) constitutes nearly 50% of heart failure cases.
- Increasing prevalence observed with aging populations.
- Often presents as acute pulmonary edema with minimal preceding symptoms.
Purpose:
- To define Heart failure with preserved ejection fraction (HFPEF).
- To highlight diagnostic tools like natriuretic peptide assays and Doppler echocardiography.
- To identify common underlying causes such as hypertensive, diabetic, or ischemic cardiomyopathy.
Summary:
- HFPEF is characterized by heart failure symptoms and an ejection fraction >=50%.
- Diagnosis is supported by elevated natriuretic peptides and echocardiographic findings.
- Common etiologies include combined cardiomyopathies, necessitating identification for management.
Impact:
- HFPEF shares a similar prognosis and hospitalization rates with systolic heart failure.
- Treatment strategies largely mirror those for systolic heart failure.
- Exclusion of diabetic patients from certain therapeutic approaches is noted.
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