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State-space approach with the maximum likelihood principle to identify the system generating time-course gene

Rui Yamaguchi1, Tomoyuki Higuchi

  • 1Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. ruiy@ims.u-tokyo.ac.jp

International Journal of Data Mining and Bioinformatics
|April 12, 2008
PubMed

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State Space Representation01:27

State Space Representation

The frequency-domain technique, commonly used in analyzing and designing feedback control systems, is effective for linear, time-invariant systems. However, it falls short when dealing with nonlinear, time-varying, and multiple-input multiple-output systems. The time-domain or state-space approach addresses these limitations by utilizing state variables to construct simultaneous, first-order differential equations, known as state equations, for an nth-order system.
Consider an RLC circuit, a...