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Updated: Jul 6, 2026

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem
Published on: December 30, 2015
[Estimation of postmortem interval with multivoxel-voxel proton 1H-MR spectroscopy]
Tian-Tong Yang1, Zhen-Wei Li, Liang Liu
1Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. yttwowo@163.com
Objective:
The purpose of our study was to evaluate the postmortem interval with multi-voxel 1H-MR spectroscopy.
Methods:
Twelve healthy rabbits were studied and the quantities of N-acetylaspartate, total choline, phosphocreatine and creatine were measured by 1H-MR spectroscopy after death at 0.5, 1, 2, 4, 6, 8, 12, 16, and 24 h.
Results:
The levels of Naa/Cr and Naa/Ch decreased following death, while the level of Ch/Cr increased initially and then decreased following death.
Conclusion:
Multi-voxel proton MR spectroscopy for Naa/Cr and Ch/Cr metabolic ratio could be used in future postmortem interval studies.
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