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Published on: November 4, 2021
Myocardial infarction with distal embolization associated with myocardial bridging in a postoperative patient: a case
1Department of Cardiology, California Pacific Medical Center, San Francisco, CA, USA. henry.huang@kp.org
Insights
Myocardial bridging can rarely cause heart attack (myocardial infarction). This case shows thrombosis and embolization due to bridging and low fluid volume, highlighting the need for hydration in at-risk patients.
Area of Science:
- Cardiology
- Vascular Biology
- Medical Case Reports
Background:
- Myocardial bridging, a congenital anomaly where a segment of a coronary artery travels through heart muscle, is rarely linked to myocardial infarction (MI).
- The precise mechanisms leading to MI in patients with myocardial bridging remain incompletely understood, with theories including superimposed thrombosis or vasospasm.
- Understanding these mechanisms is crucial for developing preventative strategies against ischemic events in affected individuals.
Observation:
- This report details an unusual case of postoperative myocardial infarction (MI).
- The MI was attributed to thrombus formation within a myocardial bridge, exacerbated by intravascular volume depletion.
- The thrombus subsequently embolized distally, causing further ischemic injury.
Findings:
- Endothelial injury within the myocardial bridge segment may create a pro-thrombotic environment.
- Intravascular volume depletion can precipitate thrombus formation and embolization in the context of myocardial bridging.
- This case illustrates a specific pathway linking myocardial bridging, volume status, and acute coronary syndrome.
Implications:
- Perioperative fluid management is critical for patients with myocardial bridging to prevent potentially life-threatening thrombotic events.
- Maintaining adequate intravascular volume may mitigate the risk of endothelial injury and subsequent thrombus formation.
- This case underscores the importance of considering myocardial bridging in the differential diagnosis of MI, particularly in postoperative settings with volume depletion.
Abstract:
Myocardial bridging is associated with myocardial infarction (MI) on rare occasions. The mechanism by which this occurs is unclear; vessel occlusion in this setting may be due to superimposed thrombosis or vasospasm. An unusual case is presented of postoperative MI from thrombosis associated with myocardial bridging and intravascular volume depletion, with subsequent distal embolization. Endothelial injury as a result of myocardial bridging may predispose to thrombus formation. To avoid MI, adequate fluid hydration is recommended during the perioperative period in patients with myocardial bridging.