Related Experiment Video
Updated: Jul 6, 2026

04:09
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Sclerotherapy: a truly minimally invasive technique
1Department of Surgery, University of California San Diego and The Vein Institute of La Jolla, California, USA. jbergan@ucsd.edu
Perspectives in Vascular Surgery and Endovascular Therapy
|April 12, 2008
Summary
Foam sclerotherapy is a safe and effective minimally invasive treatment for venous disorders. This method demonstrates superior efficacy over liquid sclerotherapy, with over 80% immediate venous occlusion and rare severe complications.
Area of Science:
- Vascular Surgery
- Minimally Invasive Procedures
- Sclerotherapy
Background:
- Venous disorder treatments are increasingly less invasive.
- Foam sclerotherapy is a promising strategy for managing venous disorders.
Purpose of the Study:
- To evaluate the efficacy and safety of foam sclerotherapy for venous disorders.
- To compare foam sclerotherapy with liquid sclerotherapy.
Main Methods:
- Review of published reports on varicose vein treatment using foam sclerotherapy.
- Analysis of prospective randomized outcome data.
Main Results:
- Foam sclerotherapy achieves immediate and primary venous occlusion rates exceeding 80%.
- Prospective randomized data suggest foam sclerotherapy is superior to liquid sclerotherapy.
- Severe complications are rare, with recurrence rates between 10% and 20%.
Conclusions:
- Foam sclerotherapy is an effective, safe, and durable short-term treatment for venous disorders.
- The procedure is quick, efficient, and cost-effective.

