Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Waiting to retrieve: possible implications for brain function.

Penelope Kostopoulos1, Michael Petrides

  • 1Montreal Neurological Institute, Neuropsychology/Cognitive Neuroscience Unit, McGill University, 3801 University Street, Montreal, H3A 2B4, QC, Canada. penelope@bic.mni.mcgill.ca

Experimental Brain Research
|April 12, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CIVET-Chimp: An automated pipeline for MRI-based cortical surface extraction in chimpanzees.

Neuroimage. Reports·2026
Same author

From transaction to transformation: a binational perspective on integrating community pharmacy into the digital health ecosystem of Southern European health systems.

Journal of pharmaceutical policy and practice·2026
Same author

Ventral temporal-frontal pathways in the human brain based on diffusion MRI tractography.

NeuroImage·2026
Same author

Barriers to vaccination delivery in community pharmacy practice: a cross-sectional study of pharmacists in Greece.

The International journal of pharmacy practice·2026
Same author

Pharmacists' perspectives on community pharmacy-based colorectal cancer prevention: a qualitative evaluation.

The International journal of pharmacy practice·2026
Same author

The inferior frontal sulcus in the chimpanzee brain: morphological examination and association with oro-facial communication.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Changes in synergy formation and modulation during cyclic finger force production tasks in female adults with dystonic cerebral palsy.

Experimental brain research·2026
Same journal

Molecular links between reelin downregulation, topoisomerase IIβ alterations, and proteins involved in Alzheimer pathology in human SH-SY5Y neuroblastoma cell line.

Experimental brain research·2026
Same journal

Motor cortex excitability during spine shape-judgment in adolescent idiopathic scoliosis: a TMS motor evoked potential study.

Experimental brain research·2026
Same journal

Trajectory dynamics and endpoint accuracy in targeted ballistic contractions.

Experimental brain research·2026
Same journal

Exploring Sevoflurane promotes hippocampal neuron mitophagy in elderly postoperative cognitive dysfunction by HSP90AA1 based on network pharmacology.

Experimental brain research·2026
Same journal

Loading modulates monosynaptic transmission from spindle primary afferents to motoneurons in humans.

Experimental brain research·2026
See all related articles

The mid-ventrolateral prefrontal cortex initiates memory retrieval early, even before a stimulus is presented. This early initiation, observed during a delay period, improves reaction times for active memory recall.

Area of Science:

  • Cognitive Neuroscience
  • Neurobiology of Memory
  • Prefrontal Cortex Function

Background:

  • The mid-ventrolateral prefrontal cortex (MVLPFC) is implicated in effortful memory retrieval.
  • Active retrieval is necessary when memory associations are not unique or constant.
  • The timing of retrieval initiation remains unclear.

Purpose of the Study:

  • To investigate whether retrieval control processes begin immediately after an instructional cue.
  • To determine if a delay period following the cue influences retrieval efficiency.
  • To examine the role of the MVLPFC in the temporal dynamics of memory retrieval.

Main Methods:

  • Participants were presented with instructional cues to retrieve specific aspects of encoded stimuli.
  • A variable delay period was introduced between the cue and the test stimulus.

Related Experiment Videos

  • Reaction times were measured for both active and automatic retrieval trials across different delay durations.

    • Main Results:

    • Active retrieval trials showed longer response times compared to automatic retrieval trials.
    • Introducing delays of up to 300 ms significantly improved reaction times by an average of 101 ms.
    • These improvements were observed across both active and automatic retrieval conditions.

    Conclusions:

    • Retrieval control mechanisms are initiated early in the post-instruction delay period, prior to stimulus presentation.
    • The MVLPFC plays a crucial role in initiating these early retrieval processes.
    • Early initiation of retrieval mechanisms optimizes subsequent memory recall performance.