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Updated: Jul 6, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Antithrombotic therapy in peripheral arterial disease
1Division of Vascular and Endovascular Surgery, Vascular Diagnostic Laboratory Services, Montefiore Medical Center and the Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY 10467, USA. elipsitz@aol.com
Managing elderly patients with peripheral arterial disease (PAD) needs a team approach. Optimal care involves coordinating with specialists and understanding antithrombotic therapies for interventions.
Area of Science:
- Vascular Medicine
- Geriatrics
- Pharmacology
Background:
- Peripheral arterial disease (PAD) is a common condition in the elderly.
- Management of PAD in older adults is complex, especially when interventions or antithrombotic therapy are involved.
- Effective care necessitates collaboration among various medical professionals.
Purpose of the Study:
- To review the pathophysiology of peripheral arterial disease (PAD).
- To summarize current data on antiplatelet and anticoagulant agents for PAD management.
- To emphasize the importance of a multidisciplinary approach in elderly PAD patients.
Main Methods:
- Literature review of PAD pathophysiology.
- Analysis of clinical trial data and guidelines on antithrombotic agents.
- Synthesis of expert recommendations for multidisciplinary care.
Main Results:
- PAD pathophysiology involves atherosclerosis and reduced blood flow.
- Antiplatelet and anticoagulant agents play crucial roles in preventing thrombotic events.
- Individualized treatment plans and clear communication are vital for optimal outcomes.
Conclusions:
- Elderly patients with PAD benefit from a coordinated, individualized care strategy.
- Understanding PAD pathophysiology and antithrombotic options is key for effective management.
- Multidisciplinary collaboration ensures comprehensive patient care and improved prognosis.
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