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Immunotherapy of chronic inflammatory demyelinating polyradiculoneuropathy
1Academic Medical Centre, Department of Neurology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. f.eftimov@amc.uva.nl
Background:
chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated disease. Current treatments are aimed at modulating the immune response to achieve remission and maintain functional status. However, many patients fail to make a long-term recovery with current treatments.
Objectives:
to review the literature on immunotherapy for CIDP.
Methods:
We used the Search Strategy of the Cochrane Neuromuscular Disease Review Group to search Medline and Embase. Randomised and non-randomised studies examining the effects of any therapeutic agent in patients with CIDP were selected. The references of relevant articles were scanned to identify additional reports of interest.
Results/Conclusion:
An overview of the different treatments for CIDP is provided. Emphasis has been placed on evidence from randomised controlled trials but open non-randomised studies are discussed if appropriate. We include a treatment algorithm and provide our views on current treatments, ongoing trials and possible directions for further research.
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