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Updated: Jul 6, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

Self-reported sleep in systemic lupus erythematosus.

Kenneth Mark Greenwood¹, Leah Lederman, Helen Dawn Lindner

¹School of Health Sciences, RMIT University, Bundoora, VIC, Australia. Ken.Greenwood@rmit.edu.au

Clinical Rheumatology

|April 15, 2008

Summary

Sleep disturbances are common in systemic lupus erythematosus (SLE), with 80.5% of patients reporting poor sleep quality. While better than those seeking treatment, SLE patients

Related Experiment Videos

Last Updated: Jul 6, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

Area of Science:

Sleep Medicine
Rheumatology
Psychology

Background:

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
Sleep disturbances are frequently reported in patients with SLE.
The prevalence and characteristics of sleep disturbances in SLE require further investigation.

Purpose of the Study:

To assess sleep disturbances in patients with SLE.
To compare sleep quality in SLE patients with a general working population and individuals seeking treatment for insomnia.

Main Methods:

A sample of 172 individuals with SLE was recruited from lupus support associations.
Two comparison groups were used: 223 adults interested in psychological treatment for sleep problems and 456 working adults.
The Pittsburgh Sleep Quality Index (PSQI) was administered to all participants to collect data on sleep parameters.

Main Results:

SLE patients reported significantly worse sleep quality across most parameters compared to the working sample.
SLE patients reported better sleep quality than the treatment-seeking sample, except for sleep onset latency.
80.5% of SLE patients scored above the threshold for poor sleep quality on the PSQI global score.

Conclusions:

Sleep disturbance is a common issue in individuals with SLE.
Sleep problems in SLE patients warrant greater clinical attention and research.
Further studies with more representative samples are needed to fully understand sleep disturbances in SLE.