Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Temporal and spatial controls of Aspergillus development.

W E Timberlake1

  • 1Department of Genetics, University of Georgia, Athens 30602.

Current Opinion in Genetics & Development
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The multiply-regulated gabA gene encoding the GABA permease of Aspergillus nidulans: a score of exons.

Molecular microbiology·1999
Same author

Increased nuclear traffic chaos in hyphae of Aspergillus nidulans: molecular characterization of apsB and in vivo observation of nuclear behaviour.

Molecular microbiology·1999
Same author

Agricultural genomics comes of age.

Nature biotechnology·1998
Same author

In vitro reconstruction of the Aspergillus (= Emericella) nidulans genome.

Proceedings of the National Academy of Sciences of the United States of America·1998
Same author

Loss of meiosis in Aspergillus.

Molecular biology and evolution·1996
Same author

catA, a new Aspergillus nidulans gene encoding a developmentally regulated catalase.

Current genetics·1996
Same journal

Temporal trajectories underlying adult neuronal diversity.

Current opinion in genetics & development·2026
Same journal

Transcription regulation of cell fate plasticity - from embryonic development to tissue regeneration.

Current opinion in genetics & development·2026
Same journal

Shared molecular and cellular programs during regeneration of glandular epithelia.

Current opinion in genetics & development·2026
Same journal

Lineage tracing in human cortical development.

Current opinion in genetics & development·2026
Same journal

Cis-regulatory strategies in developmental patterning.

Current opinion in genetics & development·2026
Same journal

GABAergic neuron fate specification and lineage allocation: from development to disorder.

Current opinion in genetics & development·2026
See all related articles

Researchers identified new signals and regulatory genes controlling fungal development in Aspergillus nidulans. A directed mutation revealed the morphogenetic role of a specific gene in conidiation.

Area of Science:

  • Mycology
  • Developmental Biology
  • Molecular Genetics

Background:

  • The filamentous fungus Aspergillus nidulans serves as a model organism for studying fungal development.
  • Understanding the regulation of asexual reproduction, specifically conidiophore development, is crucial for fungal biology.

Purpose of the Study:

  • To elucidate the molecular mechanisms governing the development of the conidiophore in Aspergillus nidulans.
  • To identify novel signals and regulatory genes involved in the commitment to and execution of the conidiation pathway.

Main Methods:

  • Discovery and characterization of physical and chemical signals influencing conidiation.
  • Cloning and functional analysis of positively and negatively acting developmental regulatory genes.
  • Creation of directed mutations in developmentally regulated genes to assess morphogenetic roles.

Related Experiment Videos

Main Results:

  • Identification of new environmental signals that trigger the conidiation pathway.
  • Characterization of key genes that positively regulate fungal development.
  • Evidence for the existence of genetic loci that negatively control developmental processes.
  • A directed mutation in an anonymous gene revealed its specific function in conidiophore morphogenesis.

Conclusions:

  • Significant progress has been made in understanding the complex regulatory network controlling Aspergillus nidulans development.
  • The findings highlight the interplay of external signals and internal genetic factors in fungal development.
  • Further research into these regulatory mechanisms can provide insights into broader principles of multicellular development.