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Updated: Jul 6, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
[Cigarette smoking and immunity disorder]
Iwona Pirogowicz1, Elzbieta Gwiazda, Katarzyna Hoffmann
1Katedra i Zakład Medycyny Rodzinnej, Akademii Medycznej we Wrocławiu. iwapir@wp.pl
Abstract:
Cigarette smoking addiction is one of the cardinal factors the diseases of respiratory system, cardio-vascular system and neoplasms. A part of them is the effect of immunosupression. It includes both morphologic changes (atrophia of lymphoid tissue) and cell functional disorder of the immune system. Cell-mediated response Th1-type, which is responsible for pathogens invasion, is depleted, whereas Th2-type is increased and has its effect on higher frequency of allergic diseases. Susceptibility to neoplasmatic changes is also augmented.
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