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Progress toward the synthesis of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide
J A Secrist1, P A Crooks, J A Maddry
1Organic Chemistry Department, Southern Research Institute, Birmingham, AL 35255-5305.
Nucleic Acids Symposium Series
|January 1, 1991
Abstract:
The synthesis of building blocks for the preparation of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide linkages is described. Coupling conditions for the conversion of several of these monomers to dimers are also described.