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Published on: June 2, 2014
Chronic daily headache: when to suspect meningitis
Larry E Davis1, Joanna G Katzman
1Chief Neurology Service, New Mexico VA Health Care System, 1501 San Pedro Drive SE, Albuquerque, NM 87108, USA. LEDavis@unm.edu
Abstract:
Millions of patients see physicians each year for headache, most of which are primary headaches. However, serious secondary headaches, such as meningitis, represent about 5% of children and 1% to 2% of adults seen in the emergency department for headache. A primary care or emergency department physician may initially miss individuals with bacterial meningitis. Considering meningitis as a headache cause is important because delay in the diagnosis may have adverse consequences. A careful history and physical examination are central in identifying individuals at high risk for meningitis. This article lists information that can be obtained from the patient that may be indicative of meningitis. Performing a lumbar puncture with appropriate examination of the cerebrospinal fluid (CSF) is the key to establishing the diagnosis of meningitis. This article also includes the types of meningitis that should be considered when the CSF demonstrates a pleocytosis.
Insights
Bacterial meningitis can be missed in emergency settings, leading to adverse outcomes. Early identification through careful history, physical exam, and cerebrospinal fluid (CSF) analysis is crucial for timely diagnosis and treatment.
Area of Science:
- Neurology
- Infectious Diseases
Background:
- Headaches are a common reason for medical visits, with primary headaches being most frequent.
- Serious secondary headaches, like meningitis, account for a significant percentage of emergency department visits for headache in children and adults.
- Bacterial meningitis can be initially overlooked by primary care and emergency physicians, delaying diagnosis and treatment.
Purpose of the Study:
- To highlight the importance of considering meningitis in headache differential diagnoses.
- To outline key historical and physical examination findings indicative of meningitis.
- To emphasize the diagnostic role of cerebrospinal fluid (CSF) analysis.
Main Methods:
- Review of clinical information obtainable from patient history and physical examination.
- Discussion of diagnostic criteria for meningitis.
- Guidance on interpreting cerebrospinal fluid (CSF) findings, particularly pleocytosis.
Main Results:
- Specific patient-reported symptoms and examination findings can suggest meningitis.
- Lumbar puncture with CSF examination is the definitive diagnostic test.
- CSF pleocytosis indicates inflammation and guides the differential diagnosis of meningitis types.
Conclusions:
- Prompt recognition of potential meningitis in patients presenting with headache is critical.
- A thorough clinical assessment combined with CSF analysis is essential for accurate and timely diagnosis.
- Early diagnosis of meningitis is vital to prevent severe consequences.
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