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Updated: Jul 5, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
An uncommon presentation of stroke in a child with trisomy 21
Sarah Boggs1, Selena L Hariharan
1Department of Pediatrics, Children's Hospital of The King's Daughters, Norfolk, VA 23507, USA.
Abstract:
A 3-year-old boy was presented to the emergency department with fever and refused to bear weight on his left leg. Evaluation leads to the eventual diagnosis of stroke secondary to moyamoya syndrome. This is an unusual presentation of stroke and highlights the need to expand the differential diagnosis of common presentations to include rare diseases in children with predisposing conditions. We explore the relationship between trisomy 21 and moyamoya syndrome and then briefly discuss strokes in childhood.
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