Erwin Schroedinger, Francis Crick and epigenetic stability.

Area of Science:

• Molecular and Cellular Biology
• Epigenetics
• Systems Biology
• Quantum Mechanics

Background:

• Erwin Schrodinger's seminal work, "What is Life?", profoundly influenced the trajectory of molecular and cellular biology.
• The book posed fundamental questions regarding the stability of biological order and the mechanisms underlying life at the molecular level.

Discussion:

• This essay re-examines Schrodinger's propositions through the lenses of modern epigenetics and systems biology.
• It contrasts two primary models for epigenetic stability: 'epigenetic templating' and 'systems biology' approaches.
• These models are analyzed in light of Schrodinger's original perspectives.

Key Insights:

• Epigenetic stability can be conceptualized through templating mechanisms or holistic systems biology frameworks.
• Quantum entanglement offers a potential solution to the 'problem of small numbers' that Schrodinger identified.
• This quantum phenomenon may explain the robustness of biological information and order.

Outlook:

• Integrating quantum mechanics with systems biology and epigenetics could provide a more comprehensive understanding of life's fundamental principles.
• Further research into quantum effects in biological systems may unlock new therapeutic and technological applications.
• Schrodinger's early inquiries remain relevant, guiding contemporary biological research.