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Updated: Jul 5, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Neonatal pulmonary tuberculosis evolving to a destroyed lung
L Alsina1, S Gala-Peralta, A Noguera
1Department of Paediatrics, Agrupació Sanitària Hospital Clínic, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain. lalsina@hsjdbcn.org
Insights
Neonatal tuberculosis (TB) is rare but can be devastating. Early diagnosis and treatment are crucial for newborns with suspected TB to prevent severe lung damage.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Neonatal tuberculosis (TB) is infrequent, challenging to diagnose, and often results in severe outcomes.
- While congenital TB is rare, postnatal infection is more common in neonates and young infants.
- Increasing immigration may lead to a rise in neonatal TB cases in industrialized nations.
Observation:
- This report details two cases of post-natally acquired pulmonary TB in newborns.
- Both infants experienced significant lung destruction, a rare complication in the first month of life.
Findings:
- Post-natal pulmonary TB can cause severe lung destruction in newborns, a complication seldom described in early infancy.
- A high index of clinical suspicion is necessary for at-risk pregnant women and their infants.
Implications:
- Early identification and prompt treatment of neonatal TB are vital to prevent severe morbidity.
- Healthcare providers should maintain a high index of suspicion for TB in neonates, especially those with risk factors.
Abstract:
Tuberculosis (TB) in the newborn is infrequent, difficult to diagnose and often devastating. Congenital TB is rare, with most neonates and young infants becoming infected after birth. The incidence of neonatal TB might increase in industrialised countries as a result of immigration from countries with higher TB incidence among women of childbearing age. We report two cases of post-natally acquired pulmonary TB in newborns who developed marked lung destruction, a complication of TB which has seldom been described in the first month of life. A high index of clinical suspicion is required when evaluating pregnant women at risk for TB and their ill children, as early identification and treatment can prevent the devastating consequences of TB.
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