Related Experiment Videos
Synthesis and nuclease susceptibility of alpha-oligodeoxyribonucleotide phosphorothioate
K Shinozuka1, T Morita, H Sawai
1Department of Chemistry, Faculty of Engineering, Gunma University, Kiryu City, Japan.
Nucleic Acids Symposium Series
|January 1, 1991
Abstract:
Novel DNA analog, alpha-2'-deoxyoligothymidylate phosphorothioate was conveniently synthesized via phosphoramidite solid support method. The non natural DNA analog showed enhanced stability toward enzymatic degradation.