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On the base sequences of the promoters in transcription initiation
1National Chemical Laboratory for Industry, Tsukuba Research Center, Ibaraki, Japan.
Nucleic Acids Symposium Series
|January 1, 1991
Abstract:
The base sequence of a specific DNA region identified as the promoter is investigated by means of the quantity Sr corresponding to "superdelocalizability" of oxygen ion of each phosphate for the ten DNA dimer units (XY/Y'X') and the six [(XY/Y'X') + H+] complexes. A mechanisum that the RNA polymerase can recognize its transcription site (phosphate), is proposed and applied to Escherichia coli promoters, lacUV5, recAp, rrnEp1, rrnEp2 (experimental facts).