Related Experiment Videos
Synthesis and properties of oligonucleotide derivative with P(V) porphyrin
M Kitamura1, A Nimura, K Kunimoto
1Division of Molecular Engineering, Graduate School of Engineering, Kyoto University, Japan.
Nucleic Acids Symposium Series
|January 1, 1991
Abstract:
Oligonucleotide derivatives with a P(V)tetraphenylporphyrin at the internucleotidic phosphodiester linkage were synthesized. Their interactions with the complementary oligonucleotide and pyrene-labeled oligonucleotide were investigated. Fluorescence from the porphyrin moiety was strongly quenched by the addition of the pyrene-labeled oligonucleotide and the template oligonucleotide.