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[Ceruloplasmin in patients with Duchenne muscular dystrophy]
J Reyes1, J Holmgren, M Colombo
1Universidad de Valparaíso, Instituto de Rehabilitación Infantil, Universidad de Chile, Santiago.
Revista Medica De Chile
|March 1, 1991
Abstract:
Duchenne muscular dystrophy is a well defined form of sex linked inherited muscular disease. Approximately 1/3 of cases are the product of a new mutation. We studied 20 patients with this disease and 19 heterozygous females. Ceruloplasmin levels were significantly higher in patients compared to controls. A possible protective role of this enzyme against oxydating agents may help prevent peroxydation of lipids from the smooth muscle cell membrane.