Related Experiment Video
Updated: Jul 5, 2026
09:50
Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
[Ultrasonic extraction for flavonoids from Perilla frutescens by response surface method]
Wei Wang1, Chen-huan Yu, Jie Shen
1Department of Pharmacy, Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China.
Summary
This study optimized ultrasonic extraction for Perilla frutescens flavonoids, finding optimal conditions for efficient yield. The ultrasonic method proved feasible for extracting these valuable compounds.
Area of Science:
- Phytochemistry
- Natural Product Extraction
Context:
- Perilla frutescens is a medicinal herb rich in flavonoids.
- Efficient extraction of these bioactive compounds is crucial for their utilization.
- Traditional extraction methods may be time-consuming and less efficient.
Purpose:
- To investigate and optimize the ultrasonic extraction process for Perilla frutescens flavonoids.
- To determine the optimal parameters influencing flavonoid yield.
- To evaluate the feasibility of the ultrasonic extraction method.
Summary:
- The study employed response surface methodology (RSM) to optimize ultrasonic extraction of Perilla frutescens flavonoids.
- Key factors evaluated included alcohol concentration, liquid-to-solid ratio, and extraction time.
- Optimal conditions were identified as 60% alcohol, a 15:1 liquid-to-solid ratio, and four 18-minute extraction cycles, yielding 24.65 mg/g of flavonoids.
Impact:
- Establishes an efficient and feasible method for Perilla frutescens flavonoid extraction.
- Provides optimized parameters for maximizing flavonoid yield.
- Contributes to the potential application of Perilla frutescens in pharmaceuticals and nutraceuticals.
