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[Study on the formulation and process of Da Chuan Xiong Fang pellet by extrusion-spheronization]
Yan-long Hong1, Yi Feng, De-sheng Xu
1Shuguang Hospital, Shanghai University of TCM, Shanghai 200021, China.
Objective:
To study on the formulation and process of Da Chuan Xiong Fang pellet by extrusion-spheronization.
Methods:
Based on the physical characters of active parts, the fast-release pellets of Chuan Xiong and Tian Ma were prepared separately by extrusion-spheronization. The formulation and process were studied by direct comparison. Then their characters were evaluated.
Results:
The active components could release more than 90% in 30 minutes and the pellets presented perfect sphericity and narrow diameter distribution.
Conclusion:
Pellets of TCM can be prepared by homemade extrusion-spheronization machine and the fast-release pellets show perfect sphericity and narrow diameter distribution.
