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RNA Structure

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...

RNA Structure

RNA Structure

The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...

RNA Structure

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...

RNA Interference

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...

RNA Interference

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...

Types of RNA

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...

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Related Experiment Video

Updated: Jul 5, 2026

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

Published on: August 12, 2019

The Vienna RNA websuite.

Andreas R Gruber¹, Ronny Lorenz, Stephan H Bernhart

¹Institute for Theoretical Chemistry, University of Vienna, Währingerstrasse 17, 1090 Wien, Austria.

Nucleic Acids Research

|April 22, 2008

Summary

The Vienna RNA Websuite offers tools for RNA sequence folding, design, and analysis. This resource aids researchers in predicting RNA interactions and designing sequences with specific structures.

Area of Science:

Bioinformatics
Computational Biology
Molecular Biology

Background:

The Vienna RNA package is a widely used suite of tools for RNA structure prediction and analysis.
Researchers require accessible platforms for complex RNA sequence manipulation and investigation.

Purpose of the Study:

To present the Vienna RNA Websuite, a web-based interface for the Vienna RNA package.
To provide a user-friendly platform for RNA folding, design, and analysis tasks.

Main Methods:

Web interface implementation of established Vienna RNA package programs.
Integration of tools for single and aligned sequence folding.
Inclusion of RNA-RNA interaction prediction and sequence design functionalities.
Incorporation of the barriers program for folding landscape analysis.

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Large-scale Production of Recombinant RNAs on a Circular Scaffold Using a Viroid-derived System in Escherichia coli

Published on: November 30, 2018

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Last Updated: Jul 5, 2026

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

Published on: August 12, 2019

Analyzing and Building Nucleic Acid Structures with 3DNA

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Published on: April 26, 2013

Large-scale Production of Recombinant RNAs on a Circular Scaffold Using a Viroid-derived System in Escherichia coli

Large-scale Production of Recombinant RNAs on a Circular Scaffold Using a Viroid-derived System in Escherichia coli

Published on: November 30, 2018

Utilization of LocARNA for structural RNA alignments.

Main Results:

The Vienna RNA Websuite offers a comprehensive suite of tools for RNA sequence analysis.
The platform facilitates folding of single and aligned sequences.
Prediction of RNA-RNA interactions and design of sequences with desired structures are supported.
Analysis of folding landscapes and structural RNA alignments are available.

Conclusions:

The Vienna RNA Websuite provides a valuable, freely accessible resource for the RNA research community.
The integrated tools streamline complex RNA sequence analysis and design workflows.
The web server enhances accessibility to powerful RNA bioinformatics tools.