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Intravenous versus inhalation anaesthesia for one-lung ventilation
Adriana Bassi1, Wilson Roberto Oliveira Milani, Regina El Dib
1Department of Anaesthesiology, Hospital Sírio Libanês, Rua Coronel Melo de Oliveira, 1062 ap 21A Pompéia, São Paulo, Brazil, 05011-040. adribassi@uol.com.br
The Cochrane Database of Systematic Reviews
|April 22, 2008
Summary
Current research shows no difference in patient outcomes between intravenous and inhalation anesthesia during one-lung ventilation. More standardized trials are needed to compare anesthesia methods for one-lung ventilation.
Area of Science:
- Anesthesiology
- Thoracic Surgery
Background:
- One-lung ventilation (OLV) is crucial for thoracic surgeries, enabling surgical access and preventing complications.
- Anesthesia for OLV is maintained via volatile inhalation or intravenous agents.
- The choice of anesthesia may impact patient outcomes.
Purpose of the Study:
- To evaluate the effectiveness and safety of intravenous versus inhalation anesthesia for OLV.
- To synthesize evidence from randomized controlled trials (RCTs) and quasi-RCTs.
Main Methods:
- Comprehensive literature search across multiple databases (CENTRAL, MEDLINE, EMBASE, etc.) up to June 2006.
- Inclusion of RCTs and quasi-RCTs comparing intravenous and inhalation anesthesia for OLV.
- Independent data extraction and quality assessment by two authors.
Main Results:
- Nine studies with 291 participants were included.
- Meta-analysis was not possible due to a lack of reported outcomes in the included studies.
- No significant differences in patient outcomes were identified between the two anesthesia methods.
Conclusions:
- No current evidence from RCTs demonstrates outcome differences between intravenous and inhalation anesthesia for OLV.
- Further research with standardized outcome measures (mortality, adverse events, awareness) is essential.
- Future trials should report dropouts and losses to follow-up for robust analysis.
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