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Related Experiment Video

Updated: Jul 5, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

Inhaled corticosteroids in asthma management.

Patrick O Sobande¹, Carolyn M Kercsmar

¹Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

Respiratory Care

|April 23, 2008

Summary

This review explores inhaled corticosteroids (ICS) for asthma, detailing current options, ideal drug features, delivery systems, and managing treatment resistance in specific patient groups like smokers and obese individuals.

Area of Science:

Pulmonology
Pharmacology

Background:

Asthma involves airway inflammation and hyperresponsiveness, leading to persistent symptoms.
Inhaled corticosteroids (ICS) are the primary treatment for managing asthma.
The exact pathogenesis of asthma remains incompletely understood.

Purpose of the Study:

To review current inhaled corticosteroid (ICS) therapies for asthma.
To discuss the characteristics of an ideal ICS.
To explore challenges in ICS treatment, including resistance in specific patient subgroups.

Main Methods:

Literature review of available ICS medications.
Analysis of delivery systems and dose-response relationships.
Examination of adverse effects and combination therapies.

Related Experiment Videos

Last Updated: Jul 5, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

Main Results:

Current ICS vary in features, delivery, and efficacy.
Combination therapy with long-acting beta agonists is common.
Treatment resistance in smokers and obese individuals requires further investigation.

Conclusions:

Optimizing ICS therapy requires understanding drug features, delivery, and patient-specific factors.
Addressing treatment resistance in subgroups like smokers and obese individuals is crucial.
Further research is needed to refine asthma management strategies.