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Updated: Jul 5, 2026
10:04
Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Nontuberculous mycobacterial pulmonary disease
Margaret M Johnson1, Ernest Andrew Waller, Jack P Leventhal
1Division of Pulmonary Medicine, Mayo Clinic Jacksonville, Jacksonville, Florida 32224, USA. johnson.margaret2@mayo.edu
Current Opinion in Pulmonary Medicine
|April 23, 2008
Summary
Nontuberculous mycobacterial lung disease is increasing, presenting new diagnostic and therapeutic challenges. This review covers current understanding, focusing on pathogenesis, diagnosis, and treatment decisions for this growing pulmonary disease.
Area of Science:
- Pulmonology
- Infectious Diseases
- Microbiology
Background:
- Increasing incidence of pulmonary disease caused by nontuberculous mycobacteria (NTM).
- Emergence of previously unrecognized NTM manifestations.
- Advancements in laboratory techniques enabling precise NTM identification and new species recognition.
Purpose of the Study:
- To review current understanding of nontuberculous mycobacterial pulmonary disease.
- To emphasize pathogenesis, diagnosis, and therapeutic decision-making.
- To highlight areas of clinical controversy and data inadequacy.
Main Methods:
- Review of the 2007 American Thoracic Society and Infectious Disease Society of America consensus statement.
- Integration of original investigations in the field.
- Synthesis of current knowledge on NTM lung disease.
Main Results:
- Improved understanding of NTM lung disease pathogenesis.
- Detailed description of clinical manifestations.
- Evaluation of the efficacy of medical and surgical therapies.
Conclusions:
- NTM lung disease requires careful diagnostic and therapeutic management.
- Current data inadequately address certain clinical controversies.
- Further research is needed to guide decision-making in complex cases.
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