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Updated: Aug 6, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Advanced imaging in sarcoidosis
Madia Ampey1, Daniel Steinberger2, David Perlman1
1Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine.
Advanced imaging like FDG-PET and MRI shows promise for diagnosing and managing sarcoidosis. Further research is needed to establish consensus on their clinical application and prognostic value.
Area of Science:
- Pulmonology
- Radiology
- Immunology
Background:
- Sarcoidosis diagnosis and treatment are challenging due to a lack of reliable biomarkers.
- Advanced imaging modalities offer potential for prognostic information and improved patient management.
Purpose of the Study:
- To review recent data on advanced imaging techniques for sarcoidosis assessment and management.
- To highlight the potential of these techniques in improving patient outcomes.
Main Methods:
- Review of recent literature on advanced imaging in sarcoidosis.
- Discussion of findings from Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET), MRI, and ultrasound.
- Analysis of associations between imaging findings and clinical features.
Main Results:
- FDG-PET is identifying previously unknown sarcoidosis involvement, but clinical significance lacks consensus.
- FDG activity in pulmonary sarcoidosis may correlate with disease progression.
- Liver elastography shows potential for risk stratification and noninvasive monitoring in hepatic sarcoidosis.
Conclusions:
- Advanced imaging (FDG-PET, MRI, ultrasound) holds significant potential for sarcoidosis patient outcomes.
- Lack of data and consensus hinders the integration of these techniques into routine management.
- Longitudinal cohort studies are essential to validate and standardize the application of advanced imaging in sarcoidosis.
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