[Malaria in Dakar: epidemiological clinical and parasitological aspects]

A retrospective case control study is underdone in Infections Diseases Service of Dakar (Senegal) from june 1 st, 1989 to december 31 st, 1989. 203 observations are collected on the basis of positive blood stream and blood films with Plasmodium falciparum. The authors give the epidemiological picture of the two clinical features which are: Malignant tertian (107 cases-53%) and intermittent access (96 cases-47%). Lethal risk is 12 fold higher in Malignant tertian form than in the intermittent one. Parasitemia median is below 5,000 parasites/mm3. There is no relation between parasite density and clinical pictures. Thus, they advance tumor necrosis factor's in the pathogenia as others authors did and its impact in vital prognostic.