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Updated: Jul 5, 2026

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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
A murine model of retroviral encephalopathy
Yoshitatsu Sei1, Anthony S Basile
1Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Current Protocols in Neuroscience
|April 23, 2008
Abstract:
This unit delineates the steps for production of a murine model of retroviral encephalopathy. The LP-BM5 infected mouse develops a chronic inflammation of the brain secondary to profound immune deficiency. The model is robust, develops rapidly and does not require the use of human pathogens. In addition, the behavioral and neurochemical characteristics of this model is reviewed.

