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Updated: Jul 5, 2026

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The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
Published on: July 16, 2014
Models of neuropathic pain in the rat
Gary J Bennett1, Jin Mo Chung, Marie Honore
1McGill University, Montreal, Quebec, Canada.
Current Protocols in Neuroscience
|April 23, 2008
Abstract:
There are now three models of neuropathic pain in the rat that are in widespread use: the chronic constriction injury, the partial sciatic ligation model, and the spinal nerve ligation model. The procedures to create these models and the behavioral assays used to quantify the resulting abnormal pain sensations are described in this unit.

