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Protein databases on the internet.

Dong Xu1, Ying Xu1

  • 1Oak Ridge National Laboratory, Oak Ridge, Tennessee.

Current Protocols in Protein Science
|April 23, 2008
PubMed
Summary
This summary is machine-generated.

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Protein databases are essential for modern biology, offering vast sequence and structure data. Exploring these resources aids in understanding protein relationships and functions across species.

Area of Science:

  • Molecular Biology
  • Bioinformatics
  • Genomics

Background:

  • The generation of vast amounts of protein data (structures, functions, sequences) is a hallmark of modern biology.
  • Protein databases are fundamental resources for biological research, enabling comparative analysis.
  • Existing protein databases are underutilized within the scientific community.

Purpose of the Study:

  • To provide an introductory guide to leveraging internet-based protein databases.
  • To highlight the importance of database searching as an initial step in protein studies.
  • To underscore the value of comparative analysis using protein databases for understanding biological relationships.

Main Methods:

  • Exploration of publicly available internet-based protein databases.

Related Experiment Videos

  • Review of data types available, including protein sequences, structures, and functions.
  • Discussion of secondary databases derived from experimental data for annotation and prediction.

    • Main Results:

    • Database comparisons reveal evolutionary relationships within genomes and across species.
    • Integrated use of multiple databases enhances the understanding of protein structure and function.
    • Secondary databases offer reorganized, annotated, and predicted information.

    Conclusions:

    • Protein databases are indispensable tools for deciphering protein science.
    • Effective utilization of protein databases can significantly advance biological research.
    • Further exploration and application of these databases are encouraged for the protein science community.