Long-term progression of Meniére's disease

Area of Science:

• Otolaryngology
• Neurology
• Audiology

Background:

• Meniere's disease is a chronic inner ear disorder.
• Characterized by episodic vertigo, tinnitus, hearing loss, and aural fullness.
• Long-term progression and outcomes require further investigation.

Purpose of the Study:

• To analyze the long-term progression of Meniere's disease.
• To assess changes in hearing, vestibular function, and work capacity over time.
• To identify patterns in disease development and spontaneous symptom resolution.

Main Methods:

• Retrospective analysis of 161 Meniere's disease patients.
• Minimum follow-up period of 9 years.
• Evaluation of hearing thresholds, caloric responses, vertigo frequency, and work ability.

Main Results:

• Significant functional loss, particularly in hearing and vestibular function, occurs early in the disease course.
• The incidence of bilateral Meniere's disease increases with disease duration.
• Spontaneous remission of vertigo symptoms was observed in some patients over the follow-up period.

Conclusions:

• Meniere's disease progression is characterized by early functional decline.
• Long-term follow-up reveals an increased risk of bilateral involvement.
• While progressive, Meniere's disease may exhibit spontaneous vertigo relief over time.