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Nomenclature and serology of HLA class I and class II alleles
James McCluskey1, Carmel Kanaan, Mary Diviney
1University of Melbourne and Australian Red Cross Blood Service, Melbourne, Australia.
Abstract:
This overview presents nomenclature and serology information on human leucocyte antigens, or HLA molecules, which are encoded by a cluster of genes linked on the short arm of chromosome 6. This region is known as the major histocompatibility coclass II molecules based upon their structure, tissue distribution, and source of peptide antigen, as well as upon their interactions with T cell subsets.
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