[Anaesthesia in connection with liver transplantation]

Area of Science:

• Anesthesiology
• Transplantation Surgery
• Critical Care Medicine

Context:

• Liver transplantation requires precise anesthetic management to optimize patient outcomes.
• Maintaining adequate central blood volume is crucial for preserving organ perfusion, especially in the brain.
• Cerebral oxygenation monitoring is essential during major surgical procedures like liver transplantation.

Purpose:

• To evaluate the anesthetic strategy for liver transplantation focused on maintaining central blood volume and cerebral oxygenation.
• To assess the effectiveness of normovolaemia in achieving maximal venous oxygen saturation during liver transplantation.
• To determine the quality of treatment by monitoring central blood volume and cerebral oxygenation levels.

Summary:

• The anesthetic plan for liver transplantation prioritizes maintaining central blood volume to ensure cerebral oxygenation.
• Normovolaemia, defined as a central blood volume achieving maximal venous oxygen saturation (85%), is maintained using blood components.
• Treatment quality is assessed by monitoring central blood volume via transthoracic electrical impedance and cerebral oxygenation (71%) using near-infrared spectroscopy.

Impact:

• This study provides insights into optimizing anesthetic techniques for liver transplant patients.
• Maintaining stable central blood volume and cerebral oxygenation can potentially improve surgical outcomes and reduce complications.
• The findings support the use of advanced monitoring techniques like transthoracic electrical impedance and near-infrared spectroscopy in complex surgeries.