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Updated: Jul 5, 2026

Orthotopic Liver Transplantation in Rats
Published on: July 1, 2012
[Anaesthesia in connection with liver transplantation]
Niels H Secher1, Peter Nissen, Frans Aa Swiatek
1Rigshospitalet, Anaestesiologisk Klinik, København Ø. nhsecher@rh.regionh.dk
Abstract:
The anaesthetic plan for liver transplantation focuses on maintaining central blood volume and thereby cerebral oxygenation. Normovolaemia represents a central blood volume that establishes a maximal venous oxygen saturation, and a value of 85% (78-90%) is maintained during the operation by administration of blood components. Treatment quality is expressed as a maintained central blood volume evaluated by transthoratic electrical impedance and a stable cerebral oxygenation (71% (67-82%)) as determined by near-infrared spectroscopy.
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