Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preparation of Lake Pigment from Calcium Carbonate and Cyanidin-3-O-Glucoside: Structural Characterization and Formation Mechanism.

Foods (Basel, Switzerland)·2026
Same author

Permissible Cathodic Polarization Levels for Underground Stainless Steel Structures in Cathodic Protection Systems.

Materials (Basel, Switzerland)·2026
Same author

Strategic optimization of osseous reconstruction for post-oncologic resection maxillofacial defects: a clinical outcomes analysis.

Journal of stomatology, oral and maxillofacial surgery·2026
Same author

NSUN3 promotes oral squamous cell carcinoma progression through autophagy activation and FOXO pathway modulation.

Frontiers in oncology·2026
Same author

Impact of in vitro digestion on the cytotoxicity and gut microbiota toxicity of three representative pesticides in apples.

Food research international (Ottawa, Ont.)·2026
Same author

Indigo Dye: From Ancient Extraction to Green Biomanufacturing.

Biotechnology and applied biochemistry·2026

Related Experiment Video

Updated: Jul 5, 2026

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering
08:04

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Published on: April 25, 2013

[Bionic design of articular cartilage].

Jun Qin1, Wenguang Zhang, Gang Wu

  • 1School of Mechanical Engineering, Shanghai Jiaotong University, Shanghai 200240, China.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
|April 26, 2008
PubMed
Summary

This study explores the bionic design of articular cartilage, focusing on its structure, material, and function. The research provides a foundation for developing innovative artificial joints and cartilage replacements.

More Related Videos

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
09:08

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants

Published on: May 14, 2020

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells
06:05

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Published on: July 14, 2023

Related Experiment Videos

Last Updated: Jul 5, 2026

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering
08:04

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Published on: April 25, 2013

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
09:08

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants

Published on: May 14, 2020

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells
06:05

Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells

Published on: July 14, 2023

Area of Science:

  • Biomaterials Science
  • Biomechanics
  • Bionics

Context:

  • Articular cartilage is a vital connective tissue in human synovial joints, crucial for joint function.
  • Understanding its unique biomedical, histological, and pathological characteristics is essential.
  • Key biomaterial, biomechanical, and bio-tribological properties require in-depth analysis.

Purpose:

  • To summarize the characteristics of articular cartilage from a novel bionics perspective.
  • To conduct a bionic design of articular cartilage at macro- and micro-levels.
  • To establish a bionic design model for artificial cartilage.

Summary:

  • This research reviews articular cartilage properties, including its biomedical, histological, pathological, biomaterial, biomechanical, and bio-tribological aspects.
  • A bionic design approach is applied to articular cartilage at both macro- and micro-levels, considering structure, material, and function.
  • A comprehensive bionic design model for articular cartilage is developed.

Impact:

  • This foundational research offers theoretical and practical insights for the innovation and manufacturing of new artificial joints.
  • The study aims to facilitate the development of artificial joints with a "soft-cushion bearing" feature.
  • It contributes to the advancement of bionic artificial cartilage development.