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Updated: Jul 5, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
Thrombosis, growth, recanalization, and rupture of a saccular, non-giant cerebral aneurysm
1Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202-5124, USA. mpritz@iupui.edu
Abstract:
A partly thrombosed, saccular, non-giant left internal carotid artery aneurysm was discovered during an evaluation for headaches in a 75-year-old woman. A mirror-image aneurysm of the right internal carotid artery was also found. During the course of about a year, the left-sided aneurysm thrombosed, grew to giant proportions, recanalized, and ruptured. During this same time, the right-sided aneurysm remained unchanged in size or shape. Even a saccular, non-giant, thrombosed aneurysm can be potentially dangerous. Such an aneurysm requires careful monitoring. If clinically appropriate, aneurysm treatment is indicated.
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