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Multimodality Diagnosis of Mesenteric Ischemia

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Published on: July 21, 2023

Diagnosing intestinal perforation: a new approach.

Daniele Ottinger¹, Jonathan R Swanson

¹Department of Pediatrics, Division of Neonatology, University of Virginia Children's Hospital, Charlottesville, Virginia 22901, USA.

American Journal of Perinatology

|April 26, 2008

Summary

Occult spontaneous intestinal perforation (SIP) is a serious risk for extremely low birthweight neonates. This case highlights a novel diagnostic approach for occult SIP in a growth-restricted neonate.

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Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model

Published on: February 11, 2021

Area of Science:

Neonatal Medicine
Pediatric Surgery
Gastroenterology

Background:

Spontaneous intestinal perforation (SIP) is a significant cause of morbidity in extremely low birthweight (ELBW) neonates.
Occult SIP, lacking radiographic pneumoperitoneum, typically affects neonates over two weeks old.
Diagnosis usually involves identifying intestinal contents on abdominal ultrasound.

Observation:

A 25-week gestation, growth-restricted neonate presented at 12 days of life.
The neonate exhibited signs suggestive of occult SIP.
A novel diagnostic mechanism was employed.

Findings:

The neonate was diagnosed with occult spontaneous intestinal perforation.
The diagnosis was achieved through an innovative method.
This case expands the understanding of occult SIP diagnosis in ELBW infants.

Implications:

This case may lead to earlier and more accurate diagnosis of occult SIP.
Novel diagnostic strategies could improve outcomes for critically ill neonates.
Further research into advanced diagnostic techniques for neonatal intestinal emergencies is warranted.