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Updated: Jul 5, 2026
06:27
Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
Published on: May 6, 2013
[Type 1 diabetes mellitus and pregnancy]
Airton Golbert1, Maria Amélia A Campos
1Faculdade de Medicina, Universidade Federal de Ciências da Saúde de Porto AlegreSão Paulo, SP, Brasil. agolbert@terra.com.br
Arquivos Brasileiros De Endocrinologia E Metabologia
|April 29, 2008
Summary
Advances in diabetes management have significantly improved pregnancy outcomes for women with type 1 diabetes. Careful planning and tight glucose control are crucial to prevent serious risks to both mother and fetus.
Area of Science:
- Obstetrics and Gynecology
- Endocrinology
- Maternal-Fetal Medicine
Context:
- Pregnancy in women with type 1 diabetes presents elevated risks for both the mother and the fetus.
- Historical outcomes have been poor, but recent technological advancements have led to improvements.
Purpose:
- To highlight the risks associated with pregnancy in type 1 diabetic women.
- To emphasize the importance of glucose control in mitigating these risks.
Summary:
- Normalization of blood glucose is essential to prevent congenital anomalies and spontaneous abortions.
- Maternal risks include hypoglycemia, diabetic ketoacidosis, retinopathy, hypertension, preeclampsia, UTIs, and polyhydramnios.
- Fetal risks include macrosomia and intrauterine fetal demise, particularly in late pregnancy.
Impact:
- Intensive glycemic management and preconception planning can significantly reduce maternal and fetal complications.
- Improved pregnancy outcomes underscore the effectiveness of modern diabetes care in this high-risk population.
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