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Updated: Jul 5, 2026
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Maternal suicidality and suicide risk in offspring
Thomas Bronisch1, Roselind Lieb
1Max-Planck-Institute of Psychiatry, Kraepelinstr. 10, D-80804 Munich, Germany. bronisch@mpipsykl.mpg.de
The Psychiatric Clinics of North America
|April 29, 2008
Summary
Family history significantly increases suicide risk, independent of mental health conditions. This familial link to suicidality is consistent across diverse populations and demographics.
Area of Science:
- Psychiatry
- Genetics
- Public Health
Background:
- Numerous studies indicate a strong familial link to suicide risk.
- Community studies confirm that suicidality aggregates within families, even without considering comorbidities.
Purpose of the Study:
- To examine the evidence for familial transmission of suicidality.
- To assess the consistency of this familial risk across different populations and demographics.
Main Methods:
- Review of community studies and family interview studies.
- Analysis of data independent of comorbidities like depression, anxiety, substance use, and personality disorders.
Main Results:
- Suicidality demonstrates a familial pattern, consistent across various treatment settings, age groups, and genders.
- Family studies focusing on maternal suicidality suggest a higher indication of suicide attempts in offspring of parents who attempted suicide.
Conclusions:
- A family history of suicide is a significant risk factor.
- The familial aggregation of suicidality is a robust finding, independent of common psychiatric comorbidities.
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